Kerrier vs. Bone cement (PMMA)
Bone cement (polymethyl methacrylate or PMMA) antibiotic beads are formed by mixing antibiotics, powdered acrylic and a liquid monomer. PMMA has a good degree of compatibility with animal tissue and can deliver antibiotic locally, but poses significant disadvantages when compared to absorbable materials like calcium sulfate:
| KERRIER (Medical Grade Calcium Sulfate) | Bone Cement (PMMA) |
|---|---|
| Fully absorbable | Non-absorbable – requires 2nd surgery for removal |
| Does not act as a foreign body | Potential for bacterial colonization if not removed |
| Delivers full amount of antibiotic | Delivers only partial amount of antibiotic |
| Will stop delivering antibiotic once fully absorbed | If not removed, prolonged sub therapeutic levels increase risk of antibiotic resistance |
| Low exothermic reaction | High exothermic reaction decreases the effectiveness of some antibiotics |
| Complete sterile kit for bead production | No commercial PMMA bead kit available |
For a safe, reliable solution for your infection cases - KERRIER delivers!
